Gymnema is is also known as gurmar, the destroyer of sugar. It is hypothesized that its work begins by blocking sugar receptors on the tongue. The action lasts about two hours and helps to reduce sugar cravings. It has been used for 1500 years to support proper pancreatic function and hold blood sugar in a normal range by delaying absorption of sugar. Recent research suggests that it aids regeneration of the pancreas in a manner that allows the pancreas to produce more insulin.
More importantly in terms of oral toxicity is that animal studies reported in PLoS One in 2013 showed that gymnema not only proved effective in the treatment of Candida albicans but prevented the development of hyphal forms in both C. albicans and Aspergillus sp.